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<p>ਨਵà©à¨ à¨à©à¨ ਨ੠ਪਾà¨à¨ ਹ੠à¨à¨¿ à¨à©à¨¨ TP53 ਵਿੱਠà¨à©à¨ à¨à¨¿à¨¸à¨®à¨¾à¨ ਦ੠ਪਰਿਵਰਤਨ, à¨à© p53 à¨à¨¿à¨à¨®à¨° ਸਪà©à¨°à©à¨¸à¨° ਪà©à¨°à©à¨à©à¨¨ ਨà©à©° à¨à¨¨à¨à©à¨¡ à¨à¨°à¨¦à¨¾ ਹà©, à¨à¨¿à¨¸à¨¨à©à©° ਠà¨à¨¸à¨° &#8216;à¨à©à¨¨à©à¨® ਦਾ ਸਰਪà©à¨°à¨¸à¨¤&#8217; à¨à¨¿à¨¹à¨¾ à¨à¨¾à¨à¨¦à¨¾ ਹà©, à¨à©°à¨à©à¨° ਲਿਮਫà©à¨¬à¨²à¨¾à¨¸à¨à¨¿à¨ ਲਿà¨à¨à©à¨®à©à¨ (ALL) ਨà©à©° à¨à¨²à¨¾à¨ ਲਠਸਠਤà©à¨ ਮà©à¨¸à¨¼à¨à¨² à¨à©à¨à¨¸à¨°à¨¾à¨ ਵਿੱà¨à©à¨ à¨à©±à¨ ਬਣਾ ਸà¨à¨¦à¨¾ ਹà©à¥¤</p>
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<h4 class="sub_head">ਸਠà¨à© ਹà©?</h4>
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<h4 class="sub_head">TP53 ਨà©à©° ਸਮà¨à¨£à¨¾</h4>
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<p>										à¨à©à¨ ਲà©à¨à¨¾à¨ ਵਿੱਠà¨à©à¨¨ ਦਾ à¨à©à¨à¨¸à¨° à¨à©±à¨ ਬਿਮਾਰ੠ਦ੠ਰà©à¨ª ਵਿੱਠà¨à¨¿à¨µà©à¨ ਵਧ ਸà¨à¨¦à¨¾ ਹà©, à¨à©°à¨à©à¨° ਤà©à¨ ਹਮਲਾਵਰ ਤੱà¨: ਠਧਿà¨à¨¨</p></div>
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<p>à¨à©à¨à¨¸à¨° ਦ੠ਠਣ੠ਡà©à¨°à¨¾à¨à¨µà¨°à¨¾à¨ ਵਿੱà¨à©à¨, TP53 (p53) ਸਾਰà©à¨à¨ à¨à¨¼à¨¤à¨°à¨¨à¨¾à¨ ਬਿਮਾਰà©à¨à¨ ਵਿੱਠਸਠਤà©à¨ ਵੱਧ ਠà¨à¨¸à¨° ਬਦਲ੠à¨à¨ à¨à¨¿à¨à¨®à¨° ਨà©à©° ਦਬਾà¨à¨£ ਵਾਲ੠à¨à©à¨¨ ਵà¨à©à¨ à¨à©à©à¨¹à¨¾ ਹà©à¥¤ ਹਾਲਾà¨à¨à¨¿, à¨à¨¾à¨°à¨¤ ਵਿੱਠà¨à¨¸à¨¦à© à¨à¨²à©à¨¨à¨¿à¨à¨² ਪà©à¨°à¨¸à©°à¨à¨¿à¨à¨¤à¨¾ à¨à©±à¨ ਹ੠ਠਤ੠à¨à¨¬à¨¾à¨¦à©-ਵਿਸ਼à©à¨¸à¨¼ ਬਿਮਾਰà©à¨à¨ ਦ੠ਨਮà©à¨¨à© ਦ੠ਠੰਦਰ ਠਢà©à¨à¨µà©à¨ ਰà©à¨ª ਵਿੱਠਪà©à¨°à¨¸à©°à¨à¨¿à¨ ਹà©, ਵਿà¨à©à¨²à¨à¨¸à¨¼à¨®à© ਰਮਾਸ਼ੰà¨à¨°, ਪà©à¨°à©à¨«à©à¨¸à¨° ਠਤ੠ਮà©à¨à©, à¨à©à¨à¨¸à¨° à¨à©à¨µ ਵਿà¨à¨¿à¨à¨¨ ਠਤ੠ਠਣ੠ਨਿਦਾਨ ਵਿà¨à¨¾à¨, à¨à©à¨à¨¸à¨° à¨à©°à¨¸à¨à©à¨à¨¿à¨à¨, ਡਬਲਯà©.à¨à¨.à¨.</p>
<p>à¨à¨¨à©à¨¹à¨¾à¨ ਨ੠à¨à¨¿à¨¹à¨¾ à¨à¨¿ à¨à¨¾à¨°à¨¤à© à¨à©à¨à¨¸à¨°à¨¾à¨ ਵਿੱà¨, TP53 ਤਬਦà©à¨²à©à¨à¨ à¨à¨¾à¨¸ ਤà©à¨° &#8216;ਤ੠à¨à©±à¨ ਬà©à¨ ਵਾਲà©à¨à¨ à¨à¨¤à¨°à¨¨à¨¾à¨ ਬਿਮਾਰà©à¨à¨ à¨à¨¿à¨µà©à¨ à¨à¨¿ ਮà©à©°à¨¹/ਸਿਰ ਠਤ੠à¨à¨°à¨¦à¨¨ ਦਾ à¨à©à¨à¨¸à¨°, ਪਿੱਤ੠ਦਾ à¨à©à¨à¨¸à¨°, à¨à¨¾à¨¤à© ਦਾ à¨à©à¨à¨¸à¨° ਠਤ੠ਫà©à¨«à©à¨¿à¨à¨ ਦ੠à¨à©à¨à¨¸à¨° ਵਿੱਠà¨à¨°à¨ªà©à¨° ਹà©à©°à¨¦à©à¨à¨ ਹਨ, à¨à¨¿à©±à¨¥à© à¨à¨¹ ਲà¨à¨¾à¨¤à¨¾à¨° à¨à©à¨¨à©à¨®à¨¿à¨ ਠਸਥਿਰਤਾ, ਹਮਲਾਵਰ à¨à¨¿à¨à¨®à¨° à¨à©à¨µ ਵਿà¨à¨¿à¨à¨¨ ਠਤ੠ਮਾà©à© à¨à¨²à©à¨¨à¨¿à¨à¨² ਨਤà©à¨à¨¿à¨à¨ ਨਾਲ à¨à©à©à© ਹà©à©°à¨¦à© ਹਨ। &#8220;à¨à¨¸ ਦ੠ਬਾਵà¨à©à¨¦, TP53 ਨà©à©° ਨਿਯਮਤ ਤà©à¨° &#8216;ਤ੠à¨à©à¨à¨® ਪੱਧਰà©à¨à¨°à¨¨ ਫਰà©à¨®à¨µà¨°à¨, à¨à¨²à¨¾à¨ ਦ੠ਫà©à¨¸à¨²à© ਦ੠ਮਾਰà¨à¨¾à¨, à¨à¨¾à¨ ਰਾਸ਼à¨à¨°à© à¨à©à¨à¨¸à¨° ਪà©à¨°à¨¬à©°à¨§à¨¨ à¨à¨²à¨à©à¨°à¨¿à¨¦à¨® ਵਿੱਠà¨à¨à©à¨à©à¨°à¨¿à¨¤ ਨਹà©à¨ à¨à©à¨¤à¨¾ à¨à¨¿à¨ ਹà©, à¨à© à¨à¨¿ à¨à©à¨¨à©à¨®à¨¿à¨ à¨à©à¨ ਠਤ੠à¨à¨²à©à¨¨à¨¿à¨à¨² à¨à¨ªà¨²à©à¨à©à¨¸à¨¼à¨¨ ਵਿà¨à¨à¨¾à¨° à¨à©±à¨ ਮਹੱਤਵਪà©à¨°à¨¨ ਠਨà©à¨µà¨¾à¨¦à¨ ਪਾà©à© ਨà©à©° ਦਰਸਾà¨à¨à¨¦à¨¾ ਹà©,&#8221; ਡਾ. ਵਿà¨à©à¨²à¨à¨¸à¨¼à¨®à© ਨ੠à¨à¨¿à¨¹à¨¾à¥¤</p>
<p>ਮਹੱਤਵਪà©à¨°à¨¨ ਤà©à¨° &#8216;ਤà©, TP53 à¨à©±à¨ ਠਲੱਠਬਾà¨à¨à¨®à¨¾à¨°à¨à¨° ਦ੠ਤà©à¨° ਤ੠à¨à©°à¨® ਨਹà©à¨ à¨à¨°à¨¦à¨¾ ਹà©: à¨à¨¸à¨¦à¨¾ ਠਸਲ à¨à¨²à©à¨¨à¨¿à¨à¨² ਮà©à©±à¨² à¨à¨¿à¨à¨®à¨° ਵਿਵਹਾਰ ਦ੠à¨à©±à¨ ਢà©à¨à¨µà©à¨ ਸੰਸ਼à©à¨§à¨ ਦ੠ਰà©à¨ª ਵਿੱਠà¨à¨¸à¨¦à© à¨à©à¨®à¨¿à¨à¨¾ ਵਿੱਠਹà©, à¨à¨¾à¨¸ ਤà©à¨° &#8216;ਤ੠à¨à¨¾à¨°à¨µà¨¾à¨à¨¯à©à¨ à¨à¨¨à¨à©à¨à©à¨¨à¨¿à¨ ਡਰਾà¨à¨µà¨°à¨¾à¨ ਦ੠ਮà©à¨à©à¨¦à¨à© ਵਿੱà¨, à¨à¨¹à¨¨à¨¾à¨ ਨ੠ਸਮà¨à¨¾à¨à¨à¥¤ &#8220;à¨à¨¦à¨¾à¨¹à¨°à¨£ ਵà¨à©à¨, ਫà©à¨«à©à¨¿à¨à¨ ਦ੠à¨à©à¨à¨¸à¨° ਵਿੱà¨, TP53 ਸਹਿ-ਪਰਿਵਰਤਨ EGFR-ਸੰà¨à¨¾à¨²à¨¿à¨¤ ਬਿਮਾਰ੠ਵਿੱਠà¨à¨ªà¨à¨¾à¨°à¨ ਪà©à¨°à¨¤à©à¨à©à¨°à¨¿à¨ ਠਤ੠ਬà¨à¨¾à¨ ਦ੠ਨਤà©à¨à¨¿à¨à¨ ਨà©à©° ਮਹੱਤਵਪà©à¨°à¨£ ਰà©à¨ª ਵਿੱਠਬਦਲਦਾ ਹà©, ਸਿੰà¨à¨²-à¨à©à¨¨ ਰਿਪà©à¨°à¨à¨¿à©°à¨ ਦ੠ਬà¨à¨¾à¨ à¨à¨à©à¨à©à¨°à¨¿à¨¤ à¨à©à¨¨à©à¨®à¨¿à¨ ਵਿà¨à¨à¨¿à¨ ਦ੠ਲà©à© ਨà©à©° ਦਰਸਾà¨à¨à¨¦à¨¾ ਹà©à¥¤ TP53 ਤਬਦà©à¨²à©à¨à¨ ਨà©à©° ਯà©à¨à¨¨à¨¾à¨¬à©±à¨§ ਤਰà©à¨à© ਨਾਲ ਵਿਸ਼à©à¨¸à¨¼à¨¤à¨¾ ਠਤ੠à¨à¨à©à¨à©à¨°à¨¿à¨¤ à¨à¨°à¨¨ ਦà©à¨à¨°à¨¾, ਠਸà©à¨ à¨à¨¾à¨°à¨¤à© à¨à©à¨à¨¸à¨° ਠਤ੠à¨à©à¨¬à¨°à¨¿à¨à¨¿à¨ ਡà©à¨à¨¾ ਦ੠ਵਿà¨à¨à¨¾à¨° à¨à©à¨¬à¨°à¨¿à¨à¨¿à¨ ਨਿਰਣਾà¨à¨ ਨਿਰਣਾ à¨à¨° ਸà¨à¨¦à© ਹਾà¨à¥¤ ਬਣਾà¨à¨£à¨¾, à¨à¨à¨¿à¨°à¨à¨¾à¨° à¨à©à¨à¨® ਪੱਧਰà©à¨à¨°à¨¨ ਦ੠ਸਹà©à¨²à¨¤ ਦਿੰਦਾ ਹà©, &#8220;à¨à¨²à¨¾à¨ ਸੰਬੰਧ੠ਤਰà¨à©à¨¹ ਠਤ੠ਮਰà©à¨à¨¼ ਦ੠ਨਤà©à¨à¨¿à¨à¨ ਵਿੱਠਸà©à¨§à¨¾à¨° à¨à¨° ਸà¨à¨¦à¨¾ ਹà©à¥¤&#8221;</p>
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 );
 userIdentify.then(function() if (isDeviceEnabled("large") && isNonSubcribedUser() && totalPcount.length > 0 && Number.isInteger(12) && totalPcount.length >= (11 + 3)) googletag.cmd.push(function() googletag.display('Desktop_AT_Mid04');
 );
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 );
 userIdentify.then(function() if (isDeviceEnabled("large") && isNonSubcribedUser() && totalPcount.length > 0 && Number.isInteger(15) && totalPcount.length >= (14 + 3)) googletag.cmd.push(function() googletag.display('Desktop_AT_Mid05');
 );
 );</script><!-- End DFP : /22390678/TH_Desktop_AT_Mid05, publisher: The Hindu --></div>
<div class="d-block d-sm-none "><script data-cfasync="false">
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 );
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 totalPcount = totalPcount || [];if (isDeviceEnabled("small")) var container = document.createElement("div");
 container.className = "article-ad";container.appendChild(createElementScript("div", "dfp-ad ", "Mweb_AT_Bottom01", minHeight: '330px'));
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 );
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</div>
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ਹਮਲਾਵਰ ਬਾਲਗ ਲਿਊਕੇਮੀਆ ਦੇ ਪਿੱਛੇ ਪਰਿਵਰਤਨਸ਼ੀਲ ਜੀਨਾਂ ਦਾ ਅਧਿਐਨ ਕਰਨਾ ਇਲਾਜ ਲਈ ਕੀ ਪੇਸ਼ਕਸ਼ ਕਰ ਸਕਦਾ ਹੈ
